Article
Prevalence and Spectrum of TBX5 Mutation in Patients with Lone Atrial Fibrillation.
International journal of medical sciences - 1 Jan 2016
Wang Zhan-Cheng, Ji Wen-Hui, Ruan Chang-Wu, Liu Xing-Yuan, Qiu Xing-Biao, Yuan Fang, Li Ruo-Gu, Xu Ying-Jia, Liu Xu, Huang Ru-Tai, Xue Song, Yang Yi-Qing
Abstract excerpt
Atrial fibrillation (AF), the most common type of cardiac rhythm disturbance encountered in clinical practice, is associated with substantially increased morbidity and mortality. Aggregating evidence demonstrates that abnormal cardiovascular development is involved in the pathogenesis of AF. A recent study has revealed that the TBX5 gene, which encodes a T-box transcription factor key to cardiovascular...
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