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Article

A novel NKX2.5 loss-of-function mutation responsible for familial atrial fibrillation.

International journal of molecular medicine - 1 May 2013

Huang Ri-Tai, Xue Song, Xu Ying-Jia, Zhou Min, Yang Yi-Qing

Abstract excerpt

Atrial fibrillation (AF) represents the most common form of sustained cardiac arrhythmia and accounts for substantial morbidity and mortality. Increasing evidence demonstrates that abnormal cardiovascular development is involved in the pathogenesis of AF. In this study, the coding exons and splice sites of the NKX2.5 gene, which encodes a homeodomain-containing transcription factor pivotal for normal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23525379
DOI: 10.3892/ijmm.2013.1316

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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