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Article

PRRX1 Loss-of-Function Mutations Underlying Familial Atrial Fibrillation.

Journal of the American Heart Association - 7 Dec 2021

Guo Xiao-Juan, Qiu Xing-Biao, Wang Jun, Guo Yu-Han, Yang Chen-Xi, Li Li, Gao Ri-Feng, Ke Zun-Ping, Di Ruo-Min, Sun Yu-Min, Xu Ying-Jia, Yang Yi-Qing

Abstract excerpt

Background Atrial fibrillation (AF) is the most common form of clinical cardiac dysrhythmia responsible for thromboembolic cerebral stroke, congestive heart failure, and death. Aggregating evidence highlights the strong genetic basis of AF. Nevertheless, AF is of pronounced genetic heterogeneity, and in an overwhelming majority of patients, the genetic determinants underpinning AF remain elusive. Methods and...

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Share to Atrial Fibrillation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cancer-related gene regulation

Share to Cardiac electrophysiology and arrhythmias

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Share to Homeodomain Proteins

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Identifiers

PMID: 34845933
DOI: 10.1161/JAHA.121.023517
PMCID: PMC9075371

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