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Article

PITX2c loss-of-function mutations responsible for congenital atrial septal defects.

International journal of medical sciences - 1 Jan 2013

Yuan Fang, Zhao Lan, Wang Juan, Zhang Wei, Li Xin, Qiu Xing-Biao, Li Ruo-Gu, Xu Ying-Jia, Xu Lei, Qu Xing-Kai, Fang Wei-Yi, Yang Yi-Qing

Abstract excerpt

Congenital heart disease (CHD) is the most common form of developmental anomaly and is the leading non-infectious cause of infant mortality. A growing body of evidence demonstrates that genetic risk factors are involved in the pathogenesis of CHD. However, CHD is a genetically heterogeneous disease and the genetic determinants for CHD in most patients remain unclear. In the present study, the entire coding region...

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Identifiers

PMID: 23983605
DOI: 10.7150/ijms.6809
PMCID: PMC3753420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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