Article

The potent broadly neutralizing antibody VIR-3434 controls Hepatitis B and D Virus infection and reduces HBsAg in humanized mice

2022-09-10

Abstract excerpt

<h4>Background & Aims</h4> Chronic hepatitis B is a major global public health problem, and coinfection with hepatitis delta virus (HDV) worsens disease outcome. Here, we describe a hepatitis B virus (HBV) surface antigen (HBsAg)-targeting monoclonal antibody (mAb) with the potential to promote functional cure of chronic hepatitis B and D to address this unmet medical need. <h4>Methods</h4> HBsAg-specific mAbs w...

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Literature Corpus work: 5dca264c-0fd9-5e55-82ae-85df26ec488d
DOI: 10.1101/2022.09.09.507326

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