Article
Neutralizing activity induced by the attenuated coxsackievirus B3 Sabin3-like strain against CVB3 infection.
Current microbiology - 1 Apr 2014
Jrad-Battikh Nadia, Souii Amira, Oueslati Leila, Aouni Mahjoub, Hober Didier, Gharbi Jawhar, Ben M'hadheb-Gharbi Manel
Abstract excerpt
Coxsackievirus B3 (CVB3) causes viral myocarditis, and can ultimately result in dilated cardiomyopathy. There is no vaccine available for clinical use. In the present work, we assessed whether the Sabin3-like mutant of CVB3 could induce a protective immunity against virulent CVB3 Nancy and CVB4 E2 strains in mice by both oral and intraperitoneal (IP) routes. Serum samples, taken from mice inoculated with...
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