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Article

A genetically engineered attenuated coxsackievirus B3 strain protects mice against lethal infection.

Journal of virology - 1 Jul 2005

Dan M, Chantler J K

Abstract excerpt

Coxsackievirus B3 (CVB3) is a common human pathogen that is endemic throughout the world. There is currently no vaccine available, although the virus is known to be highly lethal to newborns and has been associated with heart disease and pancreatitis in older children and adults. Previously, we showed that the virulence of CVB3 is reduced by a lysine-to-arginine substitution in the capsid protein VP2 (K2168R) or...

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Source

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Identifiers

PMID: 15994822
DOI: 10.1128/JVI.79.14.9285-9295.2005
PMCID: PMC1168767

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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