Article
Characterization of attenuated coxsackievirus B3 strains and prospects of their application as live-attenuated vaccines.
Expert opinion on biological therapy - 1 Feb 2010
Kim Dae-Sun, Nam Jae-Hwan
Abstract excerpt
Coxsackievirus strain CVB3 is widespread in the human population and causes myocarditis or pancreatitis. However, despite its clinical impact, there is no commercially available and clinically applicable prophylactic vaccine. This study examines the characteristics of attenuated CVB3 strains developed so far and their application as live-attenuated CVB3 vaccines, and discusses problems to be overcome in the...
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