Article
Differential behaviour in pancreas and heart of two coxsackievirus B3 variants.
Intervirology - 1 Jan 1993
Gómez R M, Cui X, Castagnino C G, Berría M I
Abstract excerpt
In order to characterize viral kinetics and pathogenic properties of two intratypic variants of coxsackievirus B type 3, Balb/c mice were intraperitoneally inoculated and serial samples harvested from days 2 to 28. Although both CB3o (amyocarditic) and CB3m (myocarditic) variants induced similar early infectivity titres in pancreas, only the latter led to severe acinar necrosis, followed in turn by patent...
Topics
- Animals
- Cells, Cultured
- Coxsackievirus Infections
- Enterovirus B, Human
- Genetic Variation
- Mice
- Mice, Inbred BALB C
- Myocarditis
- Organ Specificity
- Pancreatitis
- Viremia
- Virus Replication