Article
The unfolded protein response in a pair of sensory neurons promotes entry of C. elegans into dauer diapause.
Current biology : CB - 16 Dec 2013
Kulalert Warakorn, Kim Dennis H
Abstract excerpt
In response to unfavorable environmental conditions such as starvation, crowding, and elevated temperature, Caenorhabditis elegans larvae enter an alternative developmental stage known as dauer, which is characterized by adaptive changes in stress resistance and metabolism. The genetic dissection of the molecular mechanisms of the C. elegans dauer developmental decision has defined evolutionarily conserved...
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