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Article

Neuropeptide signals cell non-autonomous mitochondrial unfolded protein response.

Cell research - 1 Nov 2016

Shao Li-Wa, Niu Rong, Liu Ying

Abstract excerpt

Neurons have a central role in the systemic coordination of mitochondrial unfolded protein response (UPRmt) and the cell non-autonomous modulation of longevity. However, the mechanism by which the nervous system senses mitochondrial stress and communicates to the distal tissues to induce UPRmt remains unclear. Here we employ the tissue-specific CRISPR-Cas9 approach to disrupt mitochondrial function only in the...

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Identifiers

PMID: 27767096
DOI: 10.1038/cr.2016.118
PMCID: PMC5099867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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