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Article

Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin-28B genotypes.

Hepatology (Baltimore, Md.) - 1 Mar 2014

Honda Masao, Shirasaki Takayoshi, Shimakami Tetsuro, Sakai Akito, Horii Rika, Arai Kuniaki, Yamashita Tatsuya, Sakai Yoshio, Yamashita Taro, Okada Hikari, Murai Kazuhisa, Nakamura Mikiko, Mizukoshi Eishiro, Kaneko Shuichi

Abstract excerpt

UNLABELLED: Pretreatment up-regulation of hepatic interferon (IFN)-stimulated genes (ISGs) has a stronger association with the treatment-resistant interleukin (IL)28B minor genotype (MI; TG/GG at rs8099917) than with the treatment-sensitive IL28B major genotype (MA; TT at rs8099917). We compared the expression of ISGs in the liver and blood of 146 patients with chronic hepatitis C who received pegylated IFN and...

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Identifiers

PMID: 24311440
DOI: 10.1002/hep.26788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin-28B genotypes.PMID 24311440Read ↗

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