Article
Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin-28B genotypes.
Hepatology (Baltimore, Md.) - 1 Mar 2014
Honda Masao, Shirasaki Takayoshi, Shimakami Tetsuro, Sakai Akito, Horii Rika, Arai Kuniaki, Yamashita Tatsuya, Sakai Yoshio, Yamashita Taro, Okada Hikari, Murai Kazuhisa, Nakamura Mikiko, Mizukoshi Eishiro, Kaneko Shuichi
Abstract excerpt
UNLABELLED: Pretreatment up-regulation of hepatic interferon (IFN)-stimulated genes (ISGs) has a stronger association with the treatment-resistant interleukin (IL)28B minor genotype (MI; TG/GG at rs8099917) than with the treatment-sensitive IL28B major genotype (MA; TT at rs8099917). We compared...
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