Article
Interferon-stimulated genes are associated with peginterferon/ribavirin treatment response regardless of IL28B alleles in hepatitis C virus/HIV-coinfected patients.
AIDS (London, England) - 13 Mar 2013
Rallon Norma I, Lopez-Fernandez Luis A, Garcia Maria Isabel, Benguria Alberto, Fiorante Silvana, Soriano Vincent, Benito José M
Abstract excerpt
BACKGROUND: The interaction between interferon-stimulated genes (ISGs) expression, IL28B genotypes and hepatitis C treatment outcomes has been mainly evaluated in the liver tissue from hepatitis C virus (HCV)-monoinfected patients but with controversial results. Herein, we examined whether more easily accessible peripheral blood mononuclear cells (PBMCs) could be used for this purpose in HIV-HCV coinfected...
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