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Article

Hepatic cell-type specific gene expression better predicts HCV treatment outcome than IL28B genotype.

Gastroenterology - 1 May 2012

McGilvray Ian, Feld Jordan J, Chen Limin, Pattullo Venessa, Guindi Maha, Fischer Sandra, Borozan Ivan, Xie Gang, Selzner Nazia, Heathcote E Jenny, Siminovitch Katherine

Abstract excerpt

BACKGROUND & AIMS: Cell-type specific expression patterns of hepatic interferon-stimulated genes (ISGs) and single nucleotide polymorphisms (SNPs) near the IL28B gene are associated with response to interferon-based therapy in patients with chronic hepatitis C virus (HCV) infection. It is not kno...

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Identifiers

PMID: 22285807
DOI: 10.1053/j.gastro.2012.01.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22285807-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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