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Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment response

10 Oct 2007

Abstract excerpt

UNLABELLED: The reasons for hepatitis C treatment failure remain unknown but may be related to different host responses to therapy. In this study, we compared hepatic gene expression in patients prior to and during peginterferon and ribavirin therapy. In the on-treatment group, patients received either ribavirin for 72 hours prior to peginterferon alpha-2a injection or peginterferon alpha-2a for 24 hours, prior...

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PMID: 17929300
DOI: 10.1002/hep.21853

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