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Article

HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors.

Bioinformatics (Oxford, England) - 1 Feb 2014

Gao Chuan, Tignor Nicole L, Salit Jacqueline, Strulovici-Barel Yael, Hackett Neil R, Crystal Ronald G, Mezey Jason G

Abstract excerpt

MOTIVATION: Identification of expression Quantitative Trait Loci (eQTL), the genetic loci that contribute to heritable variation in gene expression, can be obstructed by factors that produce variation in expression profiles if these factors are unmeasured or hidden from direct analysis. METHODS: We have developed a method for Hidden Expression Factor analysis (HEFT) that identifies individual and pleiotropic...

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PMID: 24307700
DOI: 10.1093/bioinformatics/btt690
PMCID: PMC3904522

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MTRR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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