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Article

TreeMap: a structured approach to fine mapping of eQTL variants.

Bioinformatics (Oxford, England) - 23 May 2021

Liu Li, Chandrashekar Pramod, Zeng Biao, Sanderford Maxwell D, Kumar Sudhir, Gibson Greg

Abstract excerpt

MOTIVATION: Expression quantitative trait loci (eQTL) harbor genetic variants modulating gene transcription. Fine mapping of regulatory variants at these loci is a daunting task due to the juxtaposition of causal and linked variants at a locus as well as the likelihood of interactions among multiple variants. This problem is exacerbated in genes with multiple cis-acting eQTL, where superimposed effects of...

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Identifiers

PMID: 33135051
DOI: 10.1093/bioinformatics/btaa927
PMCID: PMC8150140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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