Article
Fitness cost associated with resistance to fluoroquinolones is diverse across clones of Klebsiella pneumoniae and may select for CTX-M-15 type extended-spectrum β-lactamase.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 May 2014
Tóth A, Kocsis B, Damjanova I, Kristóf K, Jánvári L, Pászti J, Csercsik R, Topf J, Szabó D, Hamar P, Nagy K, Füzi M
Abstract excerpt
Lowered fitness cost associated with resistance to fluoroquinolones was recently demonstrated to influence the clonal dynamics of methicillin-resistant Staphylococcus aureus (MRSA) in the health care setting. We investigated whether or not a similar mechanism impacts Klebsiella pneumoniae. The fitness of K. pneumoniae isolates from major international hospital clones (ST11, ST15, ST147) already showing high-level...
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