Article
Fitness cost associated with resistance to fluoroquinolones is diverse across clones of Klebsiella pneumoniae and may select for CTX-M-15 type extended-spectrum β-lactamase.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 May 2014
Tóth A, Kocsis B, Damjanova I, Kristóf K, Jánvári L, Pászti J, Csercsik R, Topf J, Szabó D, Hamar P, Nagy K, Füzi M
Abstract excerpt
Lowered fitness cost associated with resistance to fluoroquinolones was recently demonstrated to influence the clonal dynamics of methicillin-resistant Staphylococcus aureus (MRSA) in the health care setting. We investigated whether or not a similar mechanism impacts Klebsiella pneumoniae. The fi...
Topics
- Anti-Bacterial Agents
- Drug Resistance, Bacterial
- Energy Metabolism
- Fluoroquinolones
- Genotype
- Humans
- Klebsiella Infections
- Klebsiella pneumoniae
- Microbial Sensitivity Tests
- Molecular Typing