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Article

Fitness cost of fluoroquinolone resistance in Salmonella enterica serovar Typhimurium.

Journal of medical microbiology - 1 Aug 2003

Giraud Etienne, Cloeckaert Axel, Baucheron Sylvie, Mouline Christian, Chaslus-Dancla Elisabeth

Abstract excerpt

High-level fluoroquinolone (FQ) resistance is still infrequent in salmonellae, compared with other pathogenic enterobacteria. Data provided in this work support the hypothesis that the mechanisms that confer high-level FQ resistance on salmonellae have a prohibitive fitness cost and may thus limit the emergence of highly resistant clones. In vitro mutants that were highly resistant to ciprofloxacin (MIC = 8 and...

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Identifiers

PMID: 12867565
DOI: 10.1099/jmm.0.05178-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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