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Article

Varying fitness cost associated with resistance to fluoroquinolones governs clonal dynamic of methicillin-resistant Staphylococcus aureus.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Aug 2012

Horváth A, Dobay O, Kardos S, Ghidán Á, Tóth Á, Pászti J, Ungvári E, Horváth P, Nagy K, Zissman S, Füzi M

Abstract excerpt

The purpose of this study was to investigate the impact of fluoroquinolone resistance on the existence and dynamic of MRSA clones. Resistance to ciprofloxacin was induced in strains of community-acquired (CA) MRSA from various sequence types and the fitness cost suffered by mutant derivatives measured in a propagation assay. In addition, the fitness of fluoroquinolone resistant health care-associated (HA) MRSA...

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Identifiers

PMID: 22218830
DOI: 10.1007/s10096-011-1536-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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