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Article

A novel truncated form of eNOS associates with altered vascular function.

Cardiovascular research - 1 Mar 2014

Galluccio Elena, Cassina Laura, Russo Isabella, Gelmini Fabrizio, Setola Emanuela, Rampoldi Luca, Citterio Lorena, Rossodivita Alessandra, Kamami Mikel, Colombo Antonio, Alfieri Ottavio, Carini Marina, Bosi Emanuele, Trovati Mariella, Piatti Piermarco, Monti Lucilla D, Casari Giorgio

Abstract excerpt

AIMS: Nitric oxide (NO) plays a key role in vascular homeostasis and is produced by endothelial NO synthase (eNOS), encoded by NOS3 gene. We previously reported the genetic association between NOS3 rs753482-A>C polymorphism on intron 19 and coronary artery disease (CAD). In the attempt of conferring functional implication to the rs753482-A>C polymorphism, we investigated its influence on transcript maturation....

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Share to Endothelium, Vascular
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Share to Nitric Oxide Synthase Type III
Share to Polymorphism, Genetic
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Source

Identifiers

PMID: 24302629
DOI: 10.1093/cvr/cvt267

Genes

CAD
NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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