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Article

Glu298Asp variant of the endothelial nitric oxide synthase gene and acute coronary syndrome or premature coronary artery disease: A systematic review and meta-analysis.

Nitric oxide : biology and chemistry - 1 Sept 2023

Rai Himanshu, Fitzgerald Sean, Coughlan J J, Spence Mark, Colleran Roisin, Joner Michael, Byrne Robert A

Abstract excerpt

INTRODUCTION: Several published studies have reported an association between the Glu298Asp polymorphism (rs1799983), residing in the endothelial nitric oxide synthase (NOS3) gene, and lower levels of circulating nitric oxide, as well as an increased risk of coronary artery disease (CAD). However, association status of this genetic variant with acute coronary syndrome (ACS) or premature CAD (PCAD) is still...

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Identifiers

PMID: 37451608
DOI: 10.1016/j.niox.2023.07.001

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