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Article

The deleterious impact of a non-synonymous SNP on protein structure and function is apparent in hypertension.

Journal of molecular modeling - 27 Dec 2021

Sharma Kavita, Hema Kanipakam, Bhatraju Naveen Kumar, Kukreti Ritushree, Das Rajat Subhra, Gupta Mohit Dayal, Syed Mansoor Ali, Pasha M A Qadar

Abstract excerpt

Essential hypertension (EH) is a significant health issue around the globe. The indifferent therapy regimen suggests varied physiological functions due to the lifestyle and genetic presentations of an individual. The endothelial nitric oxide synthase (NOS3) gene is a crucial vascular system marker in EH that contributes significantly to the phenotype. Hence, the present study aimed to employ the candidate gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34961886
DOI: 10.1007/s00894-021-04997-6

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