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Article

Genetic influence on variation in serum uric acid in American Indians: the strong heart family study.

Human genetics - 1 Nov 2009

Voruganti V Saroja, Göring Harald H H, Mottl Amy, Franceschini Nora, Haack Karin, Laston Sandra, Almasy Laura, Fabsitz Richard R, Lee Elisa T, Best Lyle G, Devereux Richard B, Howard Barbara V, MacCluer Jean W, Comuzzie Anthony G, Umans Jason G, Cole Shelley A

Abstract excerpt

Hyperuricemia is associated with the metabolic syndrome, gout, renal and cardiovascular disease (CVD). American Indians have high rates of CVD and 25% of individuals in the strong heart family study (SHFS) have high serum uric acid levels. The aim of this study was to investigate the genetic determinants of serum uric acid variation in American Indian participants of the SHFS. A variance component decomposition...

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Identifiers

PMID: 19590895
DOI: 10.1007/s00439-009-0716-8
PMCID: PMC2784272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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