Article
Genome wide association study of uric acid in Indian population and interaction of identified variants with Type 2 diabetes.
Scientific reports - 23 Feb 2016
Giri Anil K, Banerjee Priyanka, Chakraborty Shraddha, Kauser Yasmeen, Undru Aditya, Roy Suki, Parekatt Vaisak, Ghosh Saurabh, Tandon Nikhil, Bharadwaj Dwaipayan
Abstract excerpt
Abnormal level of Serum Uric Acid (SUA) is an important marker and risk factor for complex diseases including Type 2 Diabetes. Since genetic determinant of uric acid in Indians is totally unexplored, we tried to identify common variants associated with SUA in Indians using Genome Wide Association Study (GWAS). Association of five known variants in SLC2A9 and SLC22A11 genes with SUA level in 4,834 normoglycemics...
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