Article
Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest.
BMC genetics - 23 Sept 2011
Laha Suparna, Das Shankar P, Hajra Sujata, Sanyal Kaustuv, Sinha Pratima
Abstract excerpt
BACKGROUND: Metaphase cells have short spindles for efficient bi-orientation of chromosomes. The cohesin proteins hold sister chromatids together, creating Sister Chromatid Cohesion (SCC) that helps in the maintenance of short spindle lengths in metaphase. The budding yeast protein Chl1p, which h...
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