Article
Pri-miR-34b/c rs4938723 polymorphism is associated with the risk of childhood acute lymphoblastic leukemia.
Cancer genetics - 1 Nov 2016
Hashemi Mohammad, Bahari Gholamreza, Naderi Majid, Sadeghi-Bojd Simin, Taheri Mohsen
Abstract excerpt
MicroRNAs (miRNAs), small noncoding regulatory RNAs, are key regulators of gene expression. The impact of Pri-miR-34b/c rs4938723 variant on development of various cancers is still controversial. In the present study, we examined whether a rs4938723 variant located at the promoter region of Pri-miR-34b/c is associated with childhood ALL. A total of 110 children with acute lymphoblastic leukemia (ALL) and 120...
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