Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.

PloS one - 1 Jan 2013

Crous-Bou Marta, Rennert Gad, Cuadras Daniel, Salazar Ramon, Cordero David, Saltz Rennert Hedy, Lejbkowicz Flavio, Kopelovich Levy, Monroe Lipkin Steven, Bernard Gruber Stephen, Moreno Victor

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is a leading cause of cancer death worldwide. Epidemiological risk factors for CRC included alcohol intake, which is mainly metabolized to acetaldehyde by alcohol dehydrogenase and further oxidized to acetate by aldehyde dehydrogenase; consequently, the role of genes in the alcohol metabolism pathways is of particular interest. The aim of this study is to analyze the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetaldehyde
Share to Alcohol Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alcohol Drinking

Share to Aldehyde Dehydrogenase

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to Ethanol

Share to Metabolic Networks and Pathways

Share to Oxidation-Reduction

Source

Open in PubMed Open full text

Identifiers

PMID: 24282520
DOI: 10.1371/journal.pone.0080158
PMCID: PMC3839967

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.PMID 24282520Read ↗

Association between ALDH2 and ADH1B Polymorphisms and the Risk for Colorectal Cancer in Koreans.Semantic proximity Read ↗

Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphisms, alcohol intake and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study.Semantic proximity Read ↗

[Role of alcohol-metabolizing enzymes gene polymorphisms and environmental exposure on colorectal cancer: a case-only study].Semantic proximity Read ↗

Polymorphisms of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 and colorectal cancer risk in Chinese males.Semantic proximity Read ↗

Alcohol intake, ADH1B and ADH1C genotypes, and the risk of colorectal cancer by sex and subsite in the Netherlands Cohort Study.Semantic proximity Read ↗

Meta-analysis of the ADH1B and ALDH2 polymorphisms and the risk of colorectal cancer in East Asians.Semantic proximity Read ↗

ALDH2 gene rs671 G > a polymorphism and the risk of colorectal cancer: A hospital-based study.Semantic proximity Read ↗

Molecular Basis of Alcohol-Related Gastric and Colon CancerSemantic proximity Read ↗

Alcohol and genetic polymorphisms: effect on risk of alcohol-related cancer.Semantic proximity Read ↗

Association of ADH1B Arg47His and ALDH2 Glu487Lys polymorphisms with risk of colorectal cancer and their interaction with environmental factors in a Chinese population.Semantic proximity Read ↗

Alcohol and colorectal cancer: the role of alcohol dehydrogenase 1C polymorphism.Semantic proximity Read ↗

Alcohol dehydrogenase and aldehyde dehydrogenase polymorphisms and colorectal cancer: the Fukuoka Colorectal Cancer Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.