Article
Alcohol dehydrogenase and aldehyde dehydrogenase polymorphisms and colorectal cancer: the Fukuoka Colorectal Cancer Study.
Cancer science - 1 Aug 2007
Yin Guang, Kono Suminori, Toyomura Kengo, Moore Malcolm A, Nagano June, Mizoue Tetsuya, Mibu Ryuichi, Tanaka Masao, Kakeji Yoshihiro, Maehara Yoshihiko, Okamura Takeshi, Ikejiri Koji, Futami Kitaroh, Yasunami Yohichi, Maekawa Takafumi, Takenaka Kenji, Ichimiya Hitoshi, Imaizumi Nobutoshi
Abstract excerpt
Alcohol dehydrogenase and aldehyde dehydrogenase are key enzymes in alcohol metabolism and therefore may be of importance to colorectal cancer development. The present case-control study was conducted to determine the influence of ADH2, ADH3 and ALDH2 polymorphisms in Fukuoka, Japan, with 685 incident cases of histologically confirmed colorectal adenocarcinomas and 778 community controls selected randomly from...
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