Article
[Role of alcohol-metabolizing enzymes gene polymorphisms and environmental exposure on colorectal cancer: a case-only study].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Oct 2013
Zhao Hao, Li Ting-ting, Yin Jie-yun, Qin Qin, Shi Yun, Tian Li-hong, Nie Shao-fa, Wang Xin, Liu Li
Abstract excerpt
OBJECTIVE: This study was designed to explore the interactions of alcohol dehydrogenase 1B (ADH1B) rs1229984, aldehyde dehydrogenase 2 (ALDH2)(rs671) and cytochrome P4502E1(CYP2E1)rs1329149 with environmental factors and the interactions between genetic factors in the susceptibility of colorectal cancer (CRC). Roles of genetic factors in the development of colorectal cancer were also studied. METHODS: With a...
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