Article
Meta-analysis of the ADH1B and ALDH2 polymorphisms and the risk of colorectal cancer in East Asians.
Internal medicine (Tokyo, Japan) - 1 Jan 2013
Guo Xu-Feng, Wang Jun, Yu Shi-Jie, Song Jia, Ji Meng-Yao, Zhang Ji-Xiang, Cao Zhuo, Wang Jing, Dong Wei-Guo
Abstract excerpt
OBJECTIVE: The aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) genes have been implicated in the development of colorectal cancer (CRC). However, the results are inconsistent. In this study, a meta-analysis was performed to assess the associations between the ALDH2 and ADH1B polymorphisms and the risk of CRC. METHODS: Relevant studies were identified using PubMed, Web of Science and CNKI up...
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