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Article

Association between ALDH2 and ADH1B Polymorphisms and the Risk for Colorectal Cancer in Koreans.

Cancer research and treatment - 1 Jul 2021

Choi Chang Kyun, Shin Min-Ho, Cho Sang-Hee, Kim Hye-Yeon, Zheng Wei, Long Jirong, Kweon Sun-Seog

Abstract excerpt

PURPOSE: Excessive alcohol consumption has been linked to an increased risk of colorectal cancer (CRC). We evaluated the association between alcohol-related genetic variants and CRC risk. MATERIALS AND METHODS: The study cohort consisted of 5,435 CRC cases and 3,553 population-based cancer-free controls. Genotype data were generated from germline DNA using the Infinium OncoArray-500K BeadChip in 2,535 cases and...

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Identifiers

PMID: 33421985
DOI: 10.4143/crt.2020.478
PMCID: PMC8291179

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