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Article

Matrix Gla protein and osteopontin genetic associations with coronary artery calcification and bone density: the CARDIA study.

Human genetics - 1 May 2005

Taylor Brent C, Schreiner Pamela J, Doherty Terence M, Fornage Myriam, Carr J Jeffrey, Sidney Steve

Abstract excerpt

A role for matrix proteins has previously been proposed in the pathogenesis of arterial calcification in the setting of atherosclerosis, and a link has been suggested between osteoporosis and arterial calcification. Our aim has been to investigate whether matrix Gla protein (MGP) T-138C, osteopontin (SPP1) T-443C, and Asp94Asp single nucleotide polymorphisms are associated with the development of arterial...

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Source

Identifiers

PMID: 15744522
DOI: 10.1007/s00439-005-1258-3

Genes

MGP
SPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Matrix Gla protein and osteopontin genetic associations with coronary artery calcification and bone density: the CARDIA study.PMID 15744522Read ↗

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