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Article

Polymorphism in the human matrix Gla protein gene is associated with the progression of vascular calcification in maintenance hemodialysis patients.

Clinical and experimental nephrology - 1 Dec 2013

Yoshikawa Kazuhiro, Abe Hideharu, Tominaga Tatsuya, Nakamura Masayuki, Kishi Seiji, Matsuura Motokazu, Nagai Kojiro, Tsuchida Kenji, Minakuchi Jun, Doi Toshio

Abstract excerpt

BACKGROUND: Matrix Gla protein (MGP) is one of the important proteins inhibiting vascular calcification (VC). Single nucleotide polymorphisms (SNPs) located in the promoter and coding regions of the MGP gene affect the transcriptional activity. In this study, we investigated the relationship between the SNPs and progression of VC in patients undergoing maintenance hemodialysis (MHD). METHODS: This was a...

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Source

Identifiers

PMID: 23504408
DOI: 10.1007/s10157-013-0785-9

Genes

MGP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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