Article
The role of Matrix Gla Protein gene variants (G-7 A and T-138 C) in susceptibility to ischemic stroke: a case-control study.
Molecular biology reports - 3 Apr 2026
Yildiz Mustafa, Kocer Kaya Damla Duru, Segmen Hatice, Sipahi Tammam, Budak Metin
Abstract excerpt
BACKGROUND: Matrix Gla Protein (MGP) plays a critical role in vascular calcification and extracellular matrix regulation, processes implicated in cerebrovascular pathology. This study aimed to evaluate the potential association between two MGP gene single nucleotide polymorphisms (SNPs), G-7 A (rs1800801) and T-138 C (rs1800802), and susceptibility to ischemic stroke. METHODS AND RESULTS: A total of 230...
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