CALU polymorphism A29809G affects calumenin availability involving vascular calcification.

doi:10.1016/j.yjmcc.2015.03.015

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Article

CALU polymorphism A29809G affects calumenin availability involving vascular calcification.

Journal of molecular and cellular cardiology - 1 May 2015

Jover Eva, Marín Francisco, Quintana Míriam, Pérez-Andreu Joaquín, Hurtado José Antonio, Rodríguez Cristina, Martínez-González José, González-Conejero Rocío, Valdés Mariano, Hernández-Romero Diana

Abstract excerpt

Calumenin inhibits gamma-carboxylation of matrix-Gla-protein preventing BMP2-dependent calcification. Our aim was to explore the clinical relevance and functionality of the CALU polymorphism rs1043550, and the relationship of calumenin time-dependent expression profile with the active calcification of human vascular smooth muscle cells (hVSMC). Coronary artery calcium score and lesion severity were assessed by...

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Identifiers

PMID: 25823396
DOI: 10.1016/j.yjmcc.2015.03.015

Genes

CALU
BMP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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