Article
Resequencing three candidate genes for major depressive disorder in a Dutch cohort.
PloS one - 1 Jan 2013
Verbeek Eva C, Bevova Marianna R, Bochdanovits Zoltán, Rizzu Patrizia, Bakker Ingrid M C, Uithuisje Tiny, De Geus Eco J, Smit Johannes H, Penninx Brenda W, Boomsma Dorret I, Hoogendijk Witte J G, Heutink Peter
Abstract excerpt
Major depressive disorder (MDD) is a psychiatric disorder, characterized by periods of low mood of more than two weeks, loss of interest in normally enjoyable activities and behavioral changes. MDD is a complex disorder and does not have a single genetic cause. In 2009 a genome wide association study (GWAS) was performed on the Dutch GAIN-MDD cohort. Many of the top signals of this GWAS mapped to a region...
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