The PCLO gene and depressive disorders: replication in a population-based study.

doi:10.1093/hmg/ddp529

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Article

The PCLO gene and depressive disorders: replication in a population-based study.

Human molecular genetics - 15 Feb 2010

Hek Karin, Mulder Cornelis L, Luijendijk Hendrika J, van Duijn Cornelia M, Hofman Albert, Uitterlinden André G, Tiemeier Henning

Abstract excerpt

Previous genome-wide association analysis revealed a new putative candidate gene for major depression: the PCLO gene. Replication in one population-based cohort did not yield genome-wide significance and further replication efforts in clinical studies were unsuccessful. We aimed to validate the association of single-nucleotide polymorphism (SNP) rs2522833 in the PCLO gene with depression in the Rotterdam Study, a...

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PMID: 19942622
DOI: 10.1093/hmg/ddp529

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PCLO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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