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Article

Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2014

Vergadi Eleni, Vaporidi Katerina, Theodorakis Emmanuel E, Doxaki Christina, Lagoudaki Eleni, Ieronymaki Eleftheria, Alexaki Vassilia I, Helms Mike, Kondili Eumorfia, Soennichsen Birte, Stathopoulos Efstathios N, Margioris Andrew N, Georgopoulos Dimitrios, Tsatsanis Christos

Abstract excerpt

Acute respiratory distress syndrome (ARDS) is a major cause of respiratory failure, with limited effective treatments available. Alveolar macrophages participate in the pathogenesis of ARDS. To investigate the role of macrophage activation in aseptic lung injury and identify molecular mediators w...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24277697
DOI: 10.4049/jimmunol.1300959

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24277697-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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