Article
Isothermal DNA amplification coupled to Au-nanoprobes for detection of mutations associated to Rifampicin resistance in Mycobacterium tuberculosis.
Journal of nanobiotechnology - 25 Nov 2013
Veigas Bruno, Pedrosa Pedro, Couto Isabel, Viveiros Miguel, Baptista Pedro V
Abstract excerpt
BACKGROUND: Tuberculosis accounted for 8.7 million new cases in 2011 and continues to be one of the leading human infectious diseases. Burdensome is the increasing rate of multi-drug resistant tuberculosis (MDRTB) and the difficulties created for treatment and public health control programs, especially in developing countries. Resistance to rifampicin (RIF), a first line antibiotic, is commonly associated with...
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