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Article

An Approach to Identifying Single-Nucleotide Mutations Using Noncovalent Associates of Gold Nanoparticles with Fluorescently Labeled Oligonucleotides.

International journal of molecular sciences - 10 Dec 2024

Epanchintseva Anna V, Gorbunova Ekaterina A, Nekrasov Mikhail D, Poletaeva Julia E, Pyshnaya Inna A

Abstract excerpt

Globally, widespread tuberculosis is one of the acute problems of healthcare. Drug-resistant forms of tuberculosis require a personalized approach to treatment. Currently, rapid methods for detecting drug resistance of Mycobacterium tuberculosis (MTB) to some antituberculosis drugs are often used and involve optical, electrochemical, or PCR-based assays. Despite the large number of these assays, it is necessary...

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PMID: 39768995
DOI: 10.3390/ijms252413230

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