Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Simultaneous drug resistance detection and genotyping of Mycobacterium tuberculosis using a low-density hydrogel microarray.

The Journal of antimicrobial chemotherapy - 1 Jun 2016

Zimenkov Danila V, Kulagina Elena V, Antonova Olga V, Zhuravlev Viacheslav Yu, Gryadunov Dmitry A

Abstract excerpt

BACKGROUND: Nucleic acid amplification tests are widely used in TB diagnostics. Priority tasks in their development consist of increasing the specificity and sensitivity of the detection of resistance to a wide spectrum of anti-TB drugs. METHODS: We developed a multiplexed assay allowing the detection of 116 drug resistance-determining mutations in the rpoB, katG, inhA, ahpC, gyrA, gyrB, rrs, eis and embB genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Bacterial
Share to Genotyping Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microarray Analysis

Share to Molecular Diagnostic Techniques

Share to Mycobacterium tuberculosis

Share to Russia

Share to Sensitivity and Specificity

Share to Tuberculosis, Multidrug-Resistant

Source

Identifiers

PMID: 26929267
DOI: 10.1093/jac/dkw015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Simultaneous drug resistance detection and genotyping of Mycobacterium tuberculosis using a low-density hydrogel microarray.PMID 26929267Read ↗

Rapid detection of resistance in Mycobacterium tuberculosis: a review discussing molecular approaches.Semantic proximity Read ↗

Development of multiplex assay for rapid characterization of Mycobacterium tuberculosis.Semantic proximity Read ↗

Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.Semantic proximity Read ↗

Simplified microarray system for simultaneously detecting rifampin, isoniazid, ethambutol, and streptomycin resistance markers in Mycobacterium tuberculosis.Semantic proximity Read ↗

A rapid, accurate, and low-cost method for detecting Mycobacterium tuberculosis and its drug-resistant genes in pulmonary tuberculosis: Applications of MassARRAY DNA mass spectrometrySemantic proximity Read ↗

Detection of streptomycin and quinolone resistance in Mycobacterium tuberculosis by a low-density DNA array.Semantic proximity Read ↗

The Analysis of Drug-Resistant Gene Mutations of Mycobacterium tuberculosis by GeneChip in Lianyungang, China.Semantic proximity Read ↗

Detection of Beijing strains of MDR M. tuberculosis and their association with drug resistance mutations in katG, rpoB, and embB genes.Semantic proximity Read ↗

New multiplex PCR for rapid detection of isoniazid-resistant Mycobacterium tuberculosis clinical isolates.Semantic proximity Read ↗

Detection of mutations in Mycobacterium tuberculosis genome determining resistance to fluoroquinolones by hybridization on biological microchips.Semantic proximity Read ↗

Rapid screening of rpoB and katG mutations in Mycobacterium tuberculosis isolates by high-resolution melting curve analysis.Semantic proximity Read ↗

Integrated Microfluidic Card with TaqMan Probes and High-Resolution Melt Analysis To Detect Tuberculosis Drug Resistance Mutations across 10 GenesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.