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Article

A self-assembled deoxyribonucleic acid concatemer for sensitive detection of single nucleotide polymorphism.

Analytica chimica acta - 4 Dec 2013

Wu Wei, Chen Junhua, Fang Zhiyuan, Ge Chenchen, Xiang Zhicheng, Ouyang Chuanyan, Lie Puchang, Xiao Zhuo, Yu Luxin, Wang Lin, Zeng Lingwen

Abstract excerpt

Polymerase-free and label-free strategies for DNA detection have shown excellent sensitivity and specificity in various biological samples. Herein, we propose a method for single nucleotide polymorphism (SNP) detection by using self-assembled DNA concatemers. Capture probes, bound to magnetic beads, can joint mediator probes by T4 DNA ligase in the presence of target DNA that is complementary to the capture probe...

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PMID: 24267087
DOI: 10.1016/j.aca.2013.09.055

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BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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