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G-quadruplex embedded in semi-CHA reaction combined with invasive reaction for label-free detection of single nucleotide polymorphisms.

Talanta - 1 Dec 2024

Yang Fang, Zhang Yunshan, Huang Tuo, Qin Ziyue, Xu Shijie, Weng Lin, Huang Haowen, Li Shuang, Zhang Diming

Abstract excerpt

G-quadruplex/thioflavin T (G4/THT) is one of the ideal label-free fluorescent light-emitting elements in the field of biosensors due to its good programmability and adaptability. However, the unsatisfactory luminous efficiency of single-molecule G4/THT limits its more practical applications. Here, we developed a G4 embedded semi-catalytic hairpin assembly (G4-SCHA) reaction by rationally modifying the traditional...

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PMID: 39128314
DOI: 10.1016/j.talanta.2024.126686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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