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Article

A dynamic sandwich assay on magnetic beads for selective detection of single-nucleotide mutations at room temperature.

Biosensors & bioelectronics - 15 Aug 2017

Wang Junxiu, Xiong Guoliang, Ma Liang, Wang Shihui, Zhou Xu, Wang Lei, Xiao Lehui, Su Xin, Yu Changyuan

Abstract excerpt

Single-nucleotide mutation (SNM) has proven to be associated with a variety of human diseases. Development of reliable methods for the detection of SNM is crucial for molecular diagnosis and personalized medicine. The sandwich assays are widely used tools for detecting nucleic acid biomarkers due to their low cost and rapid signaling. However, the poor hybridization specificity of signal probe at room temperature...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28319896
DOI: 10.1016/j.bios.2017.03.023

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BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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