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Controllable Mismatched Ligation for Bioluminescence Screening of Known and Unknown Mutations.

Analytical chemistry - 16 Feb 2016

Xu Qinfeng, Huang Si-qiang, Ma Fei, Tang Bo, Zhang Chun-yang

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) are closely related to human diseases and individual drug responses, and the accurate detection of SNPs is crucial to both clinical diagnosis and development of personalized medicine. Among various SNPs detection methods, ligase detection reaction (LDR) has shown great potential due to its low detection limit and excellent specificity. However, frequent involvement of...

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PMID: 26754165
DOI: 10.1021/acs.analchem.5b04540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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