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Article

N-cadherin is a novel ERα anchor that protects against 6-OHDA damage to dopaminergic cells.

Cellular and molecular neurobiology - 1 Jan 2014

Wang Meng, Li Feng, Shi Zixiao, Liu Yaping, Wang Xiaozhou, Li Li, Gao Dianshuai

Abstract excerpt

Parkinson's disease is a neurodegenerative disorder caused by the selective loss of dopaminergic (DA) neurons. In this study, we investigated the protective roles of glial cell line-derived neurotrophic factor (GDNF) and 17β-estradiol (E2) in the neuron cell line MN9D following treatment with 6-hydroxydopamine. This result showed that phosphorylation of protein kinase B (Akt) was significantly increased in...

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Source

Identifiers

PMID: 24254198
DOI: 10.1007/s10571-013-9993-9

Genes

GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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