Article
Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth.
Cell research - 1 Feb 2011
Jiao Li, Zhang Yong, Hu Chun, Wang Yong-Gang, Huang Aijun, He Cheng
Abstract excerpt
Glial cell line-derived neurotrophic factor (GDNF) was originally recognized for its ability to promote survival of midbrain dopaminergic neurons, but it has since been demonstrated to be crucial for the survival and differentiation of many neuronal subpopulations, including motor neurons, sympathetic neurons, sensory neurons and enteric neurons. To identify possible effectors or regulators of GDNF signaling, we...
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