Article
D(2)-Dopamine receptors target regulator of G protein signaling 9-2 to detergent-resistant membrane fractions.
Journal of neurochemistry - 1 Jan 2012
Celver Jeremy, Sharma Meenakshi, Kovoor Abraham
Abstract excerpt
Detergent-resistant membranes (DRM) are thought to contain structures such as lipid rafts that are involved in compartmentalizing cell membranes. We report that the majority of D(2)-dopamine receptors (D(2)R) expressed endogenously in mouse striatum or expressed in immortalized cell-lines is found in DRM. In addition, exogenous co-expression of D(2)R in a cell line shifted the expression of regulator of G protein...
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