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Dp71Δ78-79 dystrophin mutant stimulates neurite outgrowth in PC12 cells via upregulation and phosphorylation of HspB1.

Proteomics - 1 May 2016

Merino-Jiménez Candelaria, Aragón Jorge, Ceja Víctor, Rodríguez-Martínez Griselda, Cázares-Raga Febe E, Chardonnet Solenne, Pionneau Cédric, Rendon Alvaro, Montañez Cecilia

Abstract excerpt

PC12 cells acquire a neuronal phenotype in response to nerve growth factor (NGF). However, this phenotype is more efficiently achieved when the Dp71Δ78-79 dystrophin mutant is stably expressed in PC12-C11 cells. To investigate the effect of Dp71Δ78-79 overexpression on the protein profile of PC12-C11 cells, we compared the expression profiles of undifferentiated and NGF-differentiated PC12-C11 and PC12 cells by...

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PMID: 26936078
DOI: 10.1002/pmic.201500211

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NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Dp71Δ78-79 dystrophin mutant stimulates neurite outgrowth in PC12 cells via upregulation and phosphorylation of HspB1.PMID 26936078Read ↗

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